85 Results for "

Pueraria montana (Lour.) Merr.

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "Pueraria montana (Lour.) Merr." in MCE Product Catalog:

29
Puerarin
Puerarin
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29 Publications Verification
Cat. No.: HY-N0145
CAS No.: 3681-99-0
Category:  

Pueraria edulis Pampan. Flavonoids Leguminosae Phenols Polyphenols Plants Disease Research Fields Cancer Isoflavones

Target:  

5-HT Receptor

Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption .
10
Fexaramine
Fexaramine
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10 Cited Publications
Cat. No.: HY-10912
CAS No.: 574013-66-4
Purity:  99.24%
Target:  

FXR Autophagy

Research Areas:  

Others

Fexaramine is a potent and selective FXR agonist with an EC50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors .
7
Tectorigenin
Tectorigenin
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7 Cited Publications
Cat. No.: HY-N0792
CAS No.: 548-77-6
Category:  

Flavonoids Leguminosae Pueraria lobate (Willd.) Ohwi Plants Disease Research Fields Inflammation/Immunology Cancer Isoflavones

Target:  

Others

Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth.
2
Brassinin
Brassinin
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2 Cited Publications
Cat. No.: HY-111334
CAS No.: 105748-59-2
Purity:  99.74%
Synonyms: Brassinine
Category:  

Beassica pekinensis (Lour. ) Rupr. Alkaloids Cruciferae Cosmetic Research Plants Disease Research Fields Cancer Indole Alkaloids

Target:  

Endogenous Metabolite

Brassinin is the metabolism of a phytoalexin from Beassica pekinensis (Lour. ) Rupr. .
1
Urolithin M5
Urolithin M5
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1 Cited Publications
Cat. No.: HY-N7922
CAS No.: 91485-02-8
Synonyms: Decarboxyellagic acid
Category:  

Canarium album (Lour.) Rauesch. Phenols Polyphenols Plants Burseraceae

Target:  

Influenza Virus p38 MAPK EGFR Akt Reactive Oxygen Species (ROS) Apoptosis

Urolithin M5 (Decarboxyellagic acid) is an orally active influenza virus neuraminidase inhibitor and neuroprotective agent, with IC50 values of 174.8 μM (HK68), 191.5 μM (pdm09), 243.2 μM (WSN) and 257.1 μM (PR8) against four influenza virus neuraminidases, respectively. Urolithin M5 inhibits viral neuraminidase activity, thereby blocking influenza virus replication (including oseltamivir (HY-13317)-resistant strains), protecting infected mammals from death and improving pulmonary edema. Urolithin M5 forms a hydrogen-bond stabilized complex with IGF1R, and binds to MAPK14, AKT1, NFKB1 and EGFR. Urolithin M5 reduces reactive oxygen species production, inhibits neuronal apoptosis, restores mitochondrial transmembrane potential, and promotes neurite outgrowth of damaged neuronal cells. Urolithin M5 can be used in research related to influenza virus infection and Alzheimer's disease .
1
Kakkalide
Kakkalide
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1 Cited Publications
Cat. No.: HY-N4244
CAS No.: 58274-56-9
Category:  

other families Flavonoids Monophenols Phenols Plants Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

Reactive Oxygen Species (ROS)

Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation .
1
Irisolidone
Irisolidone
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1 Cited Publications
Cat. No.: HY-N2412
CAS No.: 2345-17-7
Category:  

Neurological Disease Plants Pueraria lobata (Willd.) Ohwi var. montana (Lour.)van der Maesen Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Cancer Isoflavones

Target:  

Chloride Channel

Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM) .
2-(2-Phenylethyl)chromone
2-(2-Phenylethyl)chromone
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Cat. No.: HY-N8220
CAS No.: 61828-53-3
Synonyms: Flidersiachromone
Category:  

Thymelaeaceae Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields Aquilaria sinensis (Lour.) Spreng.

Target:  

Glycosidase

2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS· + free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases .
(-)-Syringaresinol
(-)-Syringaresinol
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Cat. No.: HY-126066
CAS No.: 6216-81-5
Purity:  99.95%
Category:  

Annona montana Macf. Lignans Phenols Polyphenols Phenylpropanoids Plants Annonaceae Disease Research Fields Cancer

Target:  

Drug Isomer NO Synthase NF-κB TNF Receptor Interleukin Related IFNAR COX CD20 CDK Bcl-2 Family Apoptosis Akt p38 MAPK GSK-3

(-)-Syringaresinol is an orally active isomer of syringaresinol (HY-N8307) found in Annona Montana. (-)-Syringaresinol exhibits antioxidant, anti-inflammatory, and anticancer activities. (-)-Syringaresinol can alleviate ulcerative colitis via the PI3K-Akt/MAPK/Wnt signaling pathway. (-)-Syringaresinol inhibits HL-60 cell proliferation by arresting the G1 phase and inducing apoptosis. (-)-Syringaresinol inhibits LPS (HY-D1056)-induced microglial activation by downregulating the NF-κB p65 signaling pathway and its interaction with ERβ, exerting anti-neuroinflammatory effects .
Glucosyringic acid
Glucosyringic acid
0 Images
Cat. No.: HY-N3953
CAS No.: 33228-65-8
Category:  

Ketones, Aldehydes, Acids Plants Saxifragaceae Saxifraga sinomontana J. T. Pan & Gornall

Target:  

Others

Glucosyringic acid is a compound isolated from Saxifraga Montana H. .
Ilexgenin A
Ilexgenin A
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Cat. No.: HY-N6255
CAS No.: 108524-94-3
Category:  

Aquifoliaceae Triterpenes Terpenoids Periploca aphylla Decne. Plants Disease Research Fields Inflammation/Immunology Cancer

Target:  

TNF Receptor

Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer .
Neotuberostemonine
Neotuberostemonine
0 Images
Cat. No.: HY-N3196
CAS No.: 143120-46-1
Category:  

Alkaloids Stemonaceae Plants Disease Research Fields Inflammation/Immunology Stemona tuberosa Lour. Indole Alkaloids

Target:  

Bacterial

Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages .
Picfeltarraenin IA
Picfeltarraenin IA
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Cat. No.: HY-N1474
CAS No.: 97230-47-2
Category:  

Infection Picria felterrae Lour. Triterpenes Terpenoids Scrophulariaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Cholinesterase (ChE)

Picfeltarraenin IA, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IA can be used for the treatment of herpes infections, cancer and inflammation .
3'-Hydroxypuerarin
3'-Hydroxypuerarin
0 Images
Cat. No.: HY-N1980
CAS No.: 117060-54-5
Category:  

other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Isoflavones

Target:  

Reactive Oxygen Species (ROS)

3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO•, total ROS scavenging activities .
(-)Clausenamide
(-)Clausenamide
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Cat. No.: HY-116753
CAS No.: 201529-58-0
Purity:  99.92%
Category:  

Clausena lansium (Lour.) Skeels Rutaceae Plants

Target:  

Amyloid-β Tau Protein

(-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD) .
Methyl 3-hydroxyoctanoate
Methyl 3-hydroxyoctanoate
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Cat. No.: HY-117201
CAS No.: 7367-87-5
Synonyms: 3-Hydroxy octanoic acid methyl ester
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Methyl 3-hydroxyoctanoate (3-Hydroxy octanoic acid methyl ester) is an ester. Methyl 3-hydroxyoctanoate can be isolated from Pineapple .
Tectorigenin 7-​O-​Xylosyl Glucoside
Tectorigenin 7-​O-​Xylosyl Glucoside
0 Images
Cat. No.: HY-N4172
CAS No.: 231288-19-0
Category:  

Flavonoids Leguminosae Other Diseases Phenols Polyphenols Plants Pueraria lobata (Willd.) Ohwi var. montana (Lour.)van der Maesen Disease Research Fields Isoflavones

Target:  

Others

Tectorigenin 7-​O-​Xylosyl Glucoside is a glycosidic isoflavone isolated from Pueraria thomsonii flower .
Ilexhainanoside D
Ilexhainanoside D
0 Images
Cat. No.: HY-N5040
CAS No.: 1137648-52-2
Category:  

Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Tabernaemontana elegans Stapf

Target:  

Others

Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
Picfeltarraenin IB
Picfeltarraenin IB
0 Images
Cat. No.: HY-N2211
CAS No.: 97230-46-1
Category:  

Infection Triterpenes Scrophularia ningpoensis Hemsl. Terpenoids Scrophulariaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Cholinesterase (ChE)

Picfeltarraenin IB, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation .
Bruceine E
Bruceine E
0 Images
Cat. No.: HY-N3015
CAS No.: 21586-90-3
Category:  

Simaroubaceae Terpenoids Metabolic Disease Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.

Target:  

Others

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .
Assay Types